MODIFICATION OF THE EFFECTS OF ARTABOTRYS ODORATISSIMUS LINN. LEAF EXTRACT ON CELL DIVISION IN RATS WITH DIETARY OIL
BANI GAJRA (BHATTACHARYYA) *
Human Genetics Unit, Centre for Advanced Study in Cell and Chromosome Research, Department of Botany, University Of Calcutta, Calcutta-700019
GEETA TALUKDER *
Human Genetics Unit, Centre for Advanced Study in Cell and Chromosome Research, Department of Botany, University Of Calcutta, Calcutta-700019
ARCHANA SHARMA *
Human Genetics Unit, Centre for Advanced Study in Cell and Chromosome Research, Department of Botany, University Of Calcutta, Calcutta-700019
*Author to whom correspondence should be addressed.
Abstract
The crude extract of Artabotry's odoratissimus leaf, known to be an antifertility agent, when orally administered to Rattus norvegicus caused alterations in the total DNA, RNA and lipid content in tissues and induced clastogenic effects in bone marrow cells modified to a significant extent with the introduction of oil in the diet of the animals.
Keywords: Chemical Cytotoxicity, Leaf extract on Rat Chromosomes