A NEW SINGLE NUCLEOTIDE POLYMORPHISM AND ONE – ALLELE SYSTEM FOR NLAIII-RELP IN EXON 6 OF LIVIN GENE

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Published: 2012-01-01

Page: 1-3


DAE-KWANG KIM *

Department of Anatomy, School of Medicine, Institute for Medical Genetics Keimyung University, Republic of Korea, Hanvit Institute for Medical Genetics, Republic of Korea

*Author to whom correspondence should be addressed.


Abstract

Livin is a member of the inhibitor apoptosis protein and overexpressed in a variety of Solid tumors and cancer cell lines, but its expression and clinical relevance are unclear. As exon 6 of the gene showed a new NlalII -RFLP, single nucleotide polymorphismwithin codon 248 in one Philippine, allele frequencies of NlalII -248 polymorphism were studied in 200 chromosomes from 100 unrelated normal Korean individuals. As a result, only one allele system, the absence of the NlalII 248 site, was detected in Koreans.

Keywords: Livin, Nlalll-RFLP, Single nucleotide polymorphism


How to Cite

KIM, D.-K. (2012). A NEW SINGLE NUCLEOTIDE POLYMORPHISM AND ONE – ALLELE SYSTEM FOR NLAIII-RELP IN EXON 6 OF LIVIN GENE. BIONATURE, 32(1), 1–3. Retrieved from https://globalpresshub.com/index.php/BN/article/view/539

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