ANTI-TUMOUR DRUGS PRODUCED BY TISSUE CULTURE : A SHORT REVIEW

Purchase PDF

Published: 1992-01-07

Page: 33-41


K. G. RAMAHAT *

Plant Biotechnology Laboratory, Department of Botany, University of Jodhpur, Jodhpur 342 001

LATA BHARDWAJ *

Plant Biotechnology Laboratory, Department of Botany, University of Jodhpur, Jodhpur 342 001

M. N. TEWARI *

Plant Biotechnology Laboratory, Department of Botany, University of Jodhpur, Jodhpur 342 001

*Author to whom correspondence should be addressed.


Abstract

Plants are the source of several important drugs including anti-tumour agents. The chemical compounds shown to possess the anti-tumour properties are from diverse chemical groups (terpenoids, steroids, alkaloids, and others). On the basis of mode of their action they are grouped as alkylating agents,  antimetabolites, spindle fibre toxins and DNA intercalating substances.  Plant tissue culture has been used an alternative to produce, and for the understanding of biosynthesis and regulation of these drugs. Anti-tumour metabolites production in Catharanthus roseusCocculus pendulusC.  hirsutus and Ochrosia ellipitica has been investigated in cultures and high alkaloid producing cell lines have been established. The pertinent information on production of antineoplastic agents through tissue culture are discussed.


How to Cite

RAMAHAT, K. G., BHARDWAJ, L., & TEWARI, M. N. (1992). ANTI-TUMOUR DRUGS PRODUCED BY TISSUE CULTURE : A SHORT REVIEW. BIONATURE, 12(1 & 2), 33–41. Retrieved from https://globalpresshub.com/index.php/BN/article/view/393

Downloads

Download data is not yet available.