CLASSIFICATION OF PRIMARY AMENORRHEA ACCORDING TO AETIOLOGY

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Published: 1999-01-02

Page: 15-22


V. LAXSHMI KALPANA *

Department of Human Genetics, Andhra University, Visakhapatnam-530 003, Andhra Pradesh, India

M. SATYANARAYANA *

Department of Human Genetics, Andhra University, Visakhapatnam-530 003, Andhra Pradesh, India

*Author to whom correspondence should be addressed.


Abstract

70 primary amenorrhea cases are taken for the present study and classified according to their aetiology. The incidence of gonadal dysgenesis is very high with 34 cases out of 70 primary amenorrhea cases with 48.57% and this is Compared to 9 other studies where the mean is 28.80. Out of 34 gonadal dysgenesis cases chromosomal abnormalities constitutes 52.89%, the biochemical abnormalities comprises 26.49% and nearly 80% of the girls with gonadal dysgenesis have either a chromosomal abnormality or a biochemical abnormality. The incidence of mullerian duct anomalies is 20 out of 70 cases of primary amenorrhea with 28.57% and this is compared with 17 other studies where mean happened to be 34.23 and there are no chromosomal abnormalities in the patients with mullerian duct anomalies. The overall incidence of testicular feminization syndrome in various 5 other studies happened to be 5.29% whereas in the present study it is 2.85%. The chromosomal studies revealed a 46,XY chromosome constitution. The same type of findings are observed in case of polycystic ovarian syndrome with 2.85% and this is compared with the 3 other studies, where mean happened to be 3.13%.

Keywords: Gonadal dysgenesis, testicular feminization syndrome, polycystic ovarian syndrome, Mullerian duct anomalies, Turner's syndrome, Hyper gonadotropic gonadism, Hypogonadotropic gonadism


How to Cite

KALPANA, V. L., & SATYANARAYANA, M. (1999). CLASSIFICATION OF PRIMARY AMENORRHEA ACCORDING TO AETIOLOGY. BIONATURE, 19(1), 15–22. Retrieved from https://globalpresshub.com/index.php/BN/article/view/356