DNA SEQUENCES DO NOT ABIDE WITH PHYLOGENETIC DISTANCES
H. K. GOSWAMI *
Institute of Genetics, C/o 24 Kaushalnagar, via Misrod, Bhopal (M.P.) 462026, India
S. C. KANG *
Division of Food, Biological and Chemical Engineering, College of Engineering, Daegu University, Gyeongsan City 712-714, Republic of Korea
RAJEEV GOSWAMI *
Division of Food, Biological and Chemical Engineering, College of Engineering, Daegu University, Gyeongsan City 712-714, Republic of Korea
RAJEEV GOSWAMI *
Institute of Genetics, C/o 24 Kaushalnagar, via Misrod, Bhopal (M.P.) 462026, India
A. K. BAJPAI *
Institute of Genetics, C/o 24 Kaushalnagar, via Misrod, Bhopal (M.P.) 462026, India
A. K. BAJPAI *
Division of Biotechnology and Molecular Genetics, Pohang, Korea
*Author to whom correspondence should be addressed.
Abstract
Resemblance of DNA stretches from rare plants' genome with many sequences in human genome may be due to the fact that these stretches might have been prevalent in biota before bifurcation of plants and animals during pre-Cambrian / Cambrian period. We have blasted 28 Ginkgo gene sequences to search homologies with in the human genome by blast gene bank data (public data base; http:/www.ncbi.nlm.nih.gov/).
DNA stretches from 15 genes exhibit a good proportion of concordance but a Ginkgo gene, L 23107, nuclear encoding chloroplast a/b binding protein mRNA complete cds remarkably shows 89% base pairs identity/homology in a row to a human gene locus cDNA clone image: 5194336. We have also found 13 genes in Ginkgo which do not show any homologous DNA stretches on blasting with the human genome. These and earlier publications on a partly sequenced genomic DNA of a rare taxon Isoetes pantii exhibiting some homologies with various comparable loci on many human chromosomes strongly opine that the DNA sequences must have had ceaselessly multiplied during early phases of evolution and got dispersed randomly in evolving organisms during pre-Cambrian/ Cambrian. This explains as to why hundreds of gene sequences have been different, distinct prominently and also many of them uniquely found conserved in variety of organisms, plants, animals including man (Homo sapiense).
Keywords: Evolutionary Genetics, Plant-Human DNA Homology, Bioinformatics, Pre-Cambrian DNA homology,, Ginkgo DNA.