CHROMOSOMAL ALTERATIONS IN RECURRENT ABORTIONS
PATRALIKA BANERJEE *
Centre of Advanced Study (Cell & Chromosome Research) Department of Botany, University of Calcutta, 35, Ballygunj Circular Road, Calcutta-700 019, India
GEETA TALUKDER *
Centre of Advanced Study (Cell & Chromosome Research) Department of Botany, University of Calcutta, 35, Ballygunj Circular Road, Calcutta-700 019, India
ARCHANA SHARMA *
Centre of Advanced Study (Cell & Chromosome Research) Department of Botany, University of Calcutta, 35, Ballygunj Circular Road, Calcutta-700 019, India
*Author to whom correspondence should be addressed.
Abstract
A chromosomal survey of 14 couples with previous histories of habitual abortions or congenitally malformed offspring, following leucocyte culture, showed an incidence of 35.7 per cent cells with breaks or fragments. The frequency of hypermodal cells was significantly higher (P 0-001) than that of the normal populations. Hypomodal cells were absent in normal controls but the incidence in habitual aborter was 5:50 percent.
Keywords: Chromosomal Alterations - Habitual Aborters, Recurrent abortions