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The current study was planned to establish reference blood biochemical values for local rabbit does in Tiaret during two successive season, on hot and cold season kept under semi-arid environment of Tiaret, Algeria. Seventy nine does, from the local population rabbits, multiperious mature female rabbits were used in this experiment (54 on hot season and 25 on cold season). The rabbits were raised in the experimental farm of the University of Tiaret in suitable conditions. About 3 ml of blood samples were collected and analyzed for the number of red blood corpuscles (RBC), hemoglobin concentration (Hb), hematocrit (Ht), average volume of redblood corpuscles (MCV) and total numbers of leukocytes (WBC), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) and platelets number using an automatic cell counter. Statistical analysis was carried out on data,significant variations were found in biochemical parametes. In conclusion, most parametes were influenced by the season.
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