HISTOPATHOLOGICAL CHANGES IN RAT TISSUES INDUCED BY LEAD ACETATE
IPSITA CHAKRABORTY (CHATTERJEE) *
Centre for Advanced Studies in Cell and Chromosome Research, Department of Botany, University of Calcutta, Calcutta-700 019
GEETA TALUKDER *
Centre for Advanced Studies in Cell and Chromosome Research, Department of Botany, University of Calcutta, Calcutta-700 019
ARCHANA SHARMA *
Centre for Advanced Studies in Cell and Chromosome Research, Department of Botany, University of Calcutta, Calcutta-700 019
*Author to whom correspondence should be addressed.
Abstract
Laboratory-bred white rats were given daily intraperitoneal injections of lead acetate at doses of 5 mg /100 g body weight and 2.5 mg /100 g body weight and sacrificed after 5, 10 and 15 days of treatment. Study of the heart, liver and kidney displayed histological evidence of exclusive cell damage correlated with evidence of lead deposition.
Keywords: Lead deposition in tissues, Histopathology, Cytotoxicity