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The study investigated proximate and anti-nutrient composition of the stem Bark of ogirisi (Newbouldia leavis) plant. Experimental laboratory design was used to analyse the plant for the presence of proximate and anti-nutrient component of the plant (Newbouldia leavis). Result of the study showed that ogirisi (Newbouldia leavis) contains saponin, ash, moisture, crude fiber, crude protein, cardic glycoside, oxalate and trypsin inhibitor in the concentration of 1.59, 85.3%, 8.56%, 5%, 49.15%, 4%, 4.310 mg and 1.162 mg respectively. Hence the study recommend that Newbouldia leavis (Ogirisi) medicinal properties should be harnessed and used for medical treatment of diseases.
Ogunlana L, Ogunlana H. Antioxidant flavonoids: structure, function and chemical usage. Alt. Med. Rev. 2012;1: 103-111.
Iwu T. Interaction of condensed tannins with selected proteins. Phytochemistry. 2011;25(7):1591-1593.
Burkill HM. The useful plants of West Tropical Africa. Royal Bot. Gard. Kew. 2014;2:458-463.
Gill W. Involvement of tannins and flavonoids in the in vitro effects of Newbouldia laevis and Zanthoxylum zanthoxyloides extracts on the exsheathment of third-stage infective larvae of gastrointestinal nematodes. Vet. Parasitol. 2015;180(3-4):292- 297.
Okeke O. Phytochemistry and hemostatic properties of some medicinal plant sold as anti-hemorrhagic in Cotonou markets (Benin). Indian J. Sci. Technol. 2013;5(8): 3105-3109.
Akunyili Y. The concept of dysregulated signal transduction and gene expression in the pathophysiology of mood disorders. Curr. Psychiat. Rev. 2012;1: 227-257.
Iwu MM. Handbook of Africa Medicinal Plants CRC Press, Inc. London. 2000; 19.
Lewis C, Manony I. Phytochemical constituents of some Nigerian medicinal plants. Afr. J. Biotechnol. 2013;4(7):685-688.
Owolabi M, Egba SI, Uzoegwu PN, Emmanuel TN, Joshua PE. Anti-sickling potential of the ethanol seed extracts of Vigna unguiculata and Vigna subterranean. Int. J. Adv. Pharm. Nanotechnol. 2011;2(3):178-181.
Ejele AE, Akujobi IA. Phytochemistry and antimicrobial potential of basic metabolities of Piper umbellatum, Piper guineense, Ocimum gratissimium and Newbouldia laevis extracts. J. Emer. Trends Eng. Appl. Sci. 2012;3(2):309-314.
Liu D. Property distributions: differences between drugs, natural products, and molecules from combinatorial chemistry. J. Chem. Infect. Compl. Sci. 2012;43:218-227.
Dandjesso L, Gbile ZO, Adesina MO. Ethnobotany. taxanomy and conservation of medicinal plants: In: The state of medicinal plant research in Nigeria. Sofowora A. O. (ed). 2012;19.
Okwu D. The chemical analysis of food, 17th ed. Churchill Livingstone, London. 2015;3-4.
Paolo K, Gill LS, Adesina MO. Ethnomedical uses of plants in Nigeria. University of Benin Press, Benin City 2010;174 -175.
Okwu U. Natural Product drug discovery: the times have never been better. Chem. Biol. 2015;14:1098-1104.
Okafor JB. Phytochemical methods: A guide to modern techniques of plant analysis. Chapman and Hall Ltd, London. 2011;279.
Trease B, Evans MC. Free radicals, antioxidants and human diseases: where are we now? J. Lab. Clinic. Med. 2012; 119:598- 620.
Nweke IU. MM (1983). Traditional Igbo medicine. Institute of African Studies, University of Nigeria, Nsukka. 2014;122-144.
Singh T. Diversity of the biosynthesis of isoprene units. Nat. Prod. Rep. 2010; 20(2):171-183.
Harrawijn M, Iwu B, Lorke D. A new approach to practical acute toxicity testing. Arch. Toxicol. 1983;55:275-287.
Robak JK, Gryglewski RI. Pytochemical, nutritional and some medical properties of some leafy vegetables consumed by Edo people of Nigeria. Afr. J. Biotechnol. 2011; 7(14):2304- 2309.
Oloyede B, Nakayama NG, Lindsey ML, Medical LH. Inhibition of the infectivity of influenza virus by tea polyphenol. Antiviral Res. 2010;21:289- 299.
Oliver B. Heterotrimeric G proteins: Organizers of transmembrane signals. Cell. 2014;80:249-257.
Malairajan G, Ogunlana OE, Ogunlana OO. In vitro assessment of antioxidant activity of Newbouldia laevis. J. Medi. P. Res. 2016;2(8):176 -179.
Robak DE, Gryglewski C. Evaluation of the chemical composition of indigenous spices and flavoring agents. Global J. Pure Applied Sci. 2013;7:455-459.
Odugbemi U, Oliver K, Bever B. Medicinal plants in tropical West Africa. Cambridge University Press, London. 2017;117-118: 168.
Ogbonnaya O. Effect of ethanol leaf extract of Newbouldia laevis on blood glucose levels of diabetic rats. Trop. J. Pharm. Res. 2015;10(3):249-254.
Jeruto S, Price KR, Johnson TI, Fenwick GR. The chemistry and biological significance of saponins in food and feeding stuffs. Crit. Rev. Food Sci. Nutr. 2011;26:22-48.
Kensil N, Trease GE, Evans WC. Phytochemical and in vitro antimicrobial assay of the leaf extract of Newbouldia laevis. Afri. J. Trad. Compl. Alternat. Med. 2016;4(4):476 - 480.
Chukwujeku, Ncube NS, Afolayan AJ, Okoh AI. Assessment techniques of antimicrobial properties of natural compounds of plant origin: current methods and future trends. African Journal of Biotechnology. 2015;7(12):1797- 1806.
Davies H. Techniques for evaluation of medicinal plant products as antimicrobial agent: Current methods and future trends. Journal of Medicinal Plants Research. 2015;4(2):104-111.
Heldt, Heldt. Industrial exploitation of microorganisms. New Delhi: I.K. International Pvt. Ltd.; 2015.
Eyong K, Folefoc G, Kuete V, Beng V, Krohn K, Hussain H, Nkengfack A, Saeftel M, Sarite S, Hoerauf A. Newbouldi aquinone A: A naphthoquinone-anthraquinone ether coupled pigment, as a potential antimicrobial and ant imalarial agent from New boul dialaevis. Phytochemistry. 2006;67(6):605-9.
Evans WC, Trease L. Trease, Evans. Pharmacognosy 14th Edition W. B. Saunders Company Limited, New York. 1999;340.
Association of Analytical Chemistry. Official Methods of Analysis of the Association of Analytical Chemists. Washington DC; 1999.