Asian Journal of Research in Medicine and Medical Science https://globalpresshub.com/index.php/AJRMMS <p><strong><img src="https://globalpresshub.com/image/free-sign.gif" alt="" width="60" height="24" /></strong></p> <p><strong>Asian Journal of Research in Medicine and Medical Science</strong> aims to publish high-quality papers in all areas of ‘medicine and medical science’. By not excluding papers on the basis of subject area, this journal facilitates the research and wishes to publish papers as long as they are technically correct and scientifically motivated. </p> en-US Thu, 14 Mar 2024 12:16:54 +0000 OJS 3.3.0.12 http://blogs.law.harvard.edu/tech/rss 60 Phytochemical Screening and Antimicrobial Evaluation of Ethanol Extract of Cola lepidota Seeds https://globalpresshub.com/index.php/AJRMMS/article/view/1967 <p><strong>Aims:</strong> The study was carried out to examine the antimicrobial activity of ethanol extract of <em>Cola lepidota </em>seeds.</p> <p><strong>Place and Duration of the Study:</strong> Samples for the study; <em>Cola lepidota</em> seeds were collected from Nto Unang Atan in Ekpenyong Atai 1, Essien Udim L.G.A., Akwa Ibom State. The samples were analyzed in the Chemistry laboratory of Akwa Ibom State University and Microbiology laboratory of University of Uyo, Akwa Ibom State, Nigeria. The work lasted for three months.</p> <p><strong>Methodology:</strong> Air-dried seeds were ground to fine powder using a manual grinding machine and were stored in an airtight container until further use. The ground sample (20 g) was extracted with 80 mL of ethanol at room temperature for 72 hours using maceration method. A qualitative phytochemical test was conducted on the ethanol extract of the seeds of monkey cola. The antimicrobial activity of the extract was evaluated for six bacteria and four fungi using the well in agar diffusion technique.</p> <p><strong>Results:</strong> The result of the phytochemical screening revealed the presence of all the phytochemical tested except tannins, anthraquinone, and resins. The moisture content and dry weight matter of the seeds were determined to be 35.87 ± 0.77% and 64.13 ± 0.77% respectively. All the pathogenic bacteria and fungi were found susceptible to the extract mostly within the extract concentrations of 400 mg/mL and 500 mg/mL; though some were inhibited at the lower concentrations of the extract. No activity was observed against <em>Pseudomonas aeruginosa</em> at all concentrations of the plant extract. Minimum inhibitory concentrations (MIC) of the extract were determined on <em>Staphylococcus aureus, Saccharomyces cerevisiae, Aspergillus flavus,</em> and <em>Aspergillus niger </em>to be 100, 350, 150, and 150 mg/mL respectively.</p> <p><strong>Conclusion:</strong> The bioactivity of the ethanol extract of <em>Cola lepidota </em>seeds may be attributed to the interaction among the phytochemicals present in the extract. <em>Cola lepidota </em>seeds that seem to be treated as waste may be harnessed into pharmaceuticals for healthcare maintenance.</p> Emaime Jimmy Uwanta, Itohowo Okon Akpan Copyright (c) 2024 Author(s). The licensee is the journal publisher. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0 ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. https://globalpresshub.com/index.php/AJRMMS/article/view/1967 Tue, 06 Feb 2024 00:00:00 +0000 Factors Influencing Utilization of Health Insurance in a Tertiary Hospital in Southeast Nigeria https://globalpresshub.com/index.php/AJRMMS/article/view/1990 <p><strong>Aims:</strong> Sixteen years after the formal sector social health insurance program (FSSHIP) was introduced for the federal civil service in Nigeria. However, there is the paucity of information on how this has affected the level of utilization and satisfaction of the enrollees in Southeast Nigeria.</p> <p>To evaluate the health services utilization among enrollees and their satisfaction with the scheme. </p> <p><strong>Methods:</strong> Data were analyzed using SPSS version 25. Descriptive statistics-logit models were used to investigate the factors influencing the satisfaction and utilization of health insurance in a tertiary hospital.</p> <p><strong>Results:</strong> The mean age of respondents was 34.0±13.4 years. The program improved the utilization of health insurance services for 60.0% of respondents. However, they have low satisfaction at 36.6% with health service delivery. Factors responsible were long waiting time (80.6%), and payment of extra cost (61.0%), with 36.0% having catastrophic health expenditure. The chi-square value of 29.3, p = 0.02, df = 4 showed a significant association between these variables and poor utilization. Logistic regression showed, females and the married, were more likely to use health services (AOR 2.21, p = 0.02, 95% CI 1.03-2.17 and AOR 4.18, p=0.02, 95% CI; 0.11- 4.60 respectively). </p> <p><strong>Conclusion:</strong> FSSHIP had some positive effects in increasing the utilization of health care. However, the low level of satisfaction in the scheme is a cause for attention for both the HMO’s and the NHIS regulators. The variables causing this should be mitigated. The operators can leverage these factors that increase utilization through public enlightenment.</p> Arodiwe Ijeoma O., Esom EA, Shu EN, Okoronkwo IL Copyright (c) 2024 Author(s). The licensee is the journal publisher. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. https://globalpresshub.com/index.php/AJRMMS/article/view/1990 Wed, 03 Apr 2024 00:00:00 +0000 Prevalence of Bacterial Vaginosis among Women Attending Gynecology Clinic of Ruhengeri Referral Hospital https://globalpresshub.com/index.php/AJRMMS/article/view/1995 <p><strong>Background:</strong> Bacterial vaginosis is among the common condition that affect reproductive tract of women worldwide. Its prevalence was found to vary worldwide. Although bacterial vaginosis prevalence is generally high in most parts of Africa and low in much of Asia and Europe.</p> <p><strong>Aim:</strong> current study aimed to study the prevalence of bacterial vaginosis among women attending Ruhengeri Referral Hospital.</p> <p><strong>Methodology:</strong> This retrospective study was carried out at Ruhengeri Referral Hospital, where data of three months (March to May 2021) from laboratory log books were used. Recorded data was analyzed by using Microsoft excel version 2016 and SPSS version 20.</p> <p><strong>Results and Discussion:</strong> The findings showed that 134(40.36%) out of 332 women were tested positive for bacterial vaginosis. It was found that bacterial vaginosis is distributed differently in reproductive aged women and post menopause woman with 40.06% and 44% respectively (P-value= 0.506). The age group of 34-44 years was observed to be more susceptible to bacterial vaginosis with 45.16% followed by age group of ≥45 years old with 44%, however, age group between 12-22 showed lower prevalence of 34.95% and group of 23-33 years shows 41.54%. Therefore, the study observed that, based on the age, bacterial vaginosis has higher prevalence in post menopause women than reproductive aged women, but they not attend laboratory at high number. In fact, they have weakened immune system. Based on this high prevalence, preventive measures and special attention should be taken to avoid bacterial vaginosis and related complications.</p> Ishimwe Alain Prudence, Clementine Yamukujije , Hiberte Migabo, Hitayezu Elyse , Uwamahoro Console , Clarisse Uwiragiye Copyright (c) 2024 Author(s). The licensee is the journal publisher. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. https://globalpresshub.com/index.php/AJRMMS/article/view/1995 Fri, 05 Apr 2024 00:00:00 +0000 Ameliorative Role of Virgin Coconut Oil on Tramadol-Induced Nephrotoxicity in Sprague-Dawley Rats https://globalpresshub.com/index.php/AJRMMS/article/view/1996 <p>This research aims to investigate the effect of Tramadol induced nephrotoxicity and the ameliorative potency of Virgin Coconut Oil (VCO) on the kidneys using Sprague-Dawley rats as experimental models. A total of 40 rats were used for the study and were grouped 1-4 (130±30g; N=10). Group 1 served as the Control group and was given 1ml of Distilled Water (DW). Groups 2-4 received 25, 50 and 100 mg/kg of Tramadol respectively for 4 weeks. Five animals were randomly selected and euthanized, and the kidneys were harvested for histology and to determine oxidative stress levels, and blood sera were used for kidney function test. The remaining rats in each group received 10 mg/kg of VCO for duration of 2 weeks and were euthanized and above parameters were determined. Results showed an increase in the MDA and decrease in SOD and CAT values in the kidney tissue for the groups administered Tramadol. There was an increase in creatinine values in the groups administered Tramadol and an overall decrease in the values of Urea and Albumin. Sections of the tramadol-treated group showed an area of inflammatory infiltration in the interstitial space while groups administered with VCO showed normal histology. There was an increase in the CAT values for the group treated with VCO. There was an increase in creatinine values in the groups administered VCO and a decrease in the values of urea. In conclusion, Tramadol had adverse effects on the kidney however upon administration of virgin coconut oil (VCO), improvement in the cytoarchitecture of the kidney and levels of the oxidant markers was recorded.</p> O. A. Adebajo, P. K. Adebajo , O. H. Ayoade , U. U. Akpan, J. H. Ojo , F. Akande Copyright (c) 2024 Author(s). The licensee is the journal publisher. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. https://globalpresshub.com/index.php/AJRMMS/article/view/1996 Fri, 05 Apr 2024 00:00:00 +0000 Psychological Effects of Infertility in Males and Females https://globalpresshub.com/index.php/AJRMMS/article/view/2006 <p>Infertility is the inability to conceive a child after trying for more than one year. However the time period varies with age. It causes distress in people individually and as a couple. Infertile couples go through many psychological problems during this journey and while some couples seek help from professionals, others do not. It is very common to go through psychological issues like anxiety, depression and insomnia in such people because every person dreams of becoming a parent one day and if that dream is not fulfilled, it is natural to be stressed. It has several consequences on the mental health of both males and females. In this article the main aspects of psychological health after getting diagnosed with infertility are discussed.</p> Sibgha Laraib, Ayesha Asad, Sammar Nathaniel Copyright (c) 2024 Author(s). The licensee is the journal publisher. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. https://globalpresshub.com/index.php/AJRMMS/article/view/2006 Thu, 11 Apr 2024 00:00:00 +0000