Asian Journal of Research in Medicine and Medical Science <p><strong><img src="" alt="" width="60" height="24" /></strong></p> <p><strong>Asian Journal of Research in Medicine and Medical Science</strong> aims to publish high-quality papers in all areas of ‘medicine and medical science’. By not excluding papers on the basis of subject area, this journal facilitates the research and wishes to publish papers as long as they are technically correct and scientifically motivated. </p> Global Press Hub en-US Asian Journal of Research in Medicine and Medical Science Amplification of Amyloid Beta Fibril Detection Based on Mediator-Encapsulated Liposomes <p><strong>Aim:</strong> Amplifying the detection of amyloid beta peptide (Aβ peptide)</p> <p><strong>Methodology:</strong> Release of ferricyanide out of the liposomes, which was induced by the interaction between the liposomes and the peptides</p> <p><strong>Findings:</strong> Detection limit was 5 pg/mL, and the linear range was 0.01 to 10 ng/mL.</p> <p><strong>Conclusion:</strong> Sensitivity of this detection was almost identical with the comparable technique such as the bioassay based on gold nanostructures.</p> <p><strong>Recommendation:</strong> Methodology developed in this study was feasible as the portable and ultrasensitive method.</p> Jin-Won Park Copyright (c) 2023 © Copyright Global Press Hub. All rights reserved. 2023-11-08 2023-11-08 20 25 Impact of Aerobic Dance and Jogging on Junior Secondary School Teachers: Blood Pressure and Body Fat Perspective <p>This study investigated the impact of aerobic dance and jogging on the blood pressure (BP) and percentage of body fat (PBF) among junior secondary school teachers in Onelga. The study employed an experimental methodology, utilising a sample size of thirty (30) teachers who were recruited at random from six junior secondary schools in Onelga. The participants were assigned at random to three groups, each comprising ten (10) teachers: the control group and two experimental groups. In addition, they had a 30-minute session of aerobic dance and jogging, during which their physiological features were assessed; the exercise lasted for 6 weeks. The results indicated that the systolic blood pressure exhibited mean differences of 13.16, 10.46, and 6.5, with a mean gain of 6.66 and 3.99. The mean difference in diastolic blood pressure was 4.89, 3.91, and 6, with a mean gain of 1.11 and 2.09. The percentage of body fat recorded the mean differences of 1.22, 1.42, and 2, whereas the mean gains were 0.78 and 0.58, respectively. These findings suggest that aerobic dance and jogging impact the blood pressure and percentage of body fat among junior secondary school teachers in Onelga. Hence, it is advisable for junior secondary school teachers in Onelga to include aerobic dance and jogging into their daily regimen in order to optimise their blood pressure and pulmonary blood flow.</p> Glory Anwuri Nwadibia Emeka Usman Mong Geraldine Umoh Amba Ekpo Copyright (c) 2023 © Copyright Global Press Hub. All rights reserved. 2023-12-30 2023-12-30 26 36 Prevalence, Risk Factors and Antifungal Susceptibility of Orofungal Infections among HIV- Positive Patients in Nnamdi Azikiwe Teaching Hospital <p>This study aimed at assessing the prevalence, risk factors and antifungal resistance profiling of oro-fungal infections and their causative organisms among HIV-positive patients in Nnamdi Azikiwe teaching hospital (NAUTH), Nnewi, Anambra State, Nigeria; a total of 180 patients who gave their consent were used for the study carried out from January 2022 to August 2022. Oral swab samples of the patients were taken with the aid of sterile swab sticks, and cultured on Sabouraud’s dextrose agar, Chrome agar and blood agar at 37°C incubation. Fungal organisms isolated were characterized accordingly using Gram stain, germ tube tests, sugar fermentation and assimilation tests, and also with fungal atlas for mold identification. ITS region molecular typing was also used to identify the top four most frequently occurring isolates. Structured questionnaires were used to obtain demographic details of the participants and for risk factors evaluation. Isolates were also evaluated for pathogenicity using haemolysis and enzyme assays. Antifungal susceptibility testing of the isolates was conducted using the disc diffusion method. Data obtained were statistically analyzed in percentages as well as with oneway analysis of variance at 95% confidence interval using the SPSS software version 22. The oro-fungi organisms isolated are <em>Candida albicans, Candida glabrata, Candida krusei, Candida tropicalis, Candid neoformans, Histoplama capsulatum </em>and <em>Aspergillus fumigatus. </em> Overall prevalence of the isolates in the participants (n=180) showed that <em>C. albicans</em> was the most prevalent isolate with an occurrence of 84.78% followed by <em>C. glabrata</em> (60.33%). <em>Cryptococcus neoformans</em> and <em>Histoplasma capsulatum</em> were the least occurring isolates with the occurrence of 6.79% and 2.99% respectively. The overall occurrence pattern was <em>C. albicans</em> &gt; <em>C. glabrata</em> &gt; <em>C. krusei</em> &gt; <em>C. tropicalis</em> &gt; <em>A. fumigatus</em> &gt; <em>C. neoformans</em> &gt; <em>H. capsulatum</em>. (Gender distribution were: NAUTH 88 male (48.89%) and 92 female (51.11%); Age range 36-45 years had the highest frequency of 37.22% while age range &gt;75 years had the lowest patient frequency of 0.56% that participated in the study, distribution based on marital status, of which married subjects accounted for 60.56% and single patients were 39.44 % frequency. Distribution based on educational level and profession, it was observed that 32.22% of patients that participated in the study had primary school education as their highest point, and they accounted for the most population that took part in the study. A 21.12% frequency that took part in the study had university degrees and accounted for the least participation frequency in the study. Artisans had the highest participation frequency of 62.22% while housewives’ participation was the least with a frequency of 5.56%. 15.56% of the participants had Hepatitis B vaccination while 100% of the participants were already participating in HAART.</p> C. Enemuoh Remigius U. Orji, Michael N. Ozoh Chinwendu C. Agu Kingsley C. Okereke, Uzoma Copyright (c) 2023 © Copyright Global Press Hub. All rights reserved. 2023-07-29 2023-07-29 12 19 Temporary Anchorage Devices (TADs) in Orthodontics: A Review <p>Hallmark of orthodontics is the important fact that there should be movement of designated teeth in the line of force intended to be in proper positions harmonious with all other hard and soft tissues and there should be absolutely no movement of any other tooth as a reaction to the force applied. This resistance to movement of the reactive teeth is called anchorage. Absolute anchorage to achieve practically seems to be next to impossible at present. But “Secure Anchorage” atleast is a prerequisite for successful treatment of various malocclusions. Routine methods of anchorage for orthodontic tooth movement involves teeth, extraoral and/or intermaxillary appliances. But these methods are still inadequate in terms of anchorage control of the reactive units and result is often unsatisfactory intra and inter-arch alignment. Skeletal anchorage in the form of temporary anchorage devices (TADs) or miniscrews, has changed the scenario of anchorage control providing maximum anchorage with minimum patient compliance and without a complicated clinical procedure. The aim of this article is to extensively discuss the historical development, design, types, clinical procedure, important factors for stability and other biologic parameters necessary for their clinical use.</p> Rajeev Sharma Deepak Mohan Soni Copyright (c) 2023 © Copyright Global Press Hub. All rights reserved. 2023-01-09 2023-01-09 1 11