Improved Faradaic Quality of Betamethasone-clotrimazole Redox Profile on A Bentonite Modified Carbon Graphite Working Electrode

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Published: 2022-03-31

Page: 243-255


Duke Omondi Orata *

Department of Chemistry, University of Nairobi, P.O.Box 30197-00100, Nairobi, Kenya.

Dorcas Gathoni Ngigi

Department of Chemistry, University of Nairobi, P.O.Box 30197-00100, Nairobi, Kenya.

David Kinuthia Kariuki

Department of Chemistry, University of Nairobi, P.O.Box 30197-00100, Nairobi, Kenya.

*Author to whom correspondence should be addressed.


Abstract

In this paper surface modified electrodes interfaced with cyclic voltammetry for data capture, has been used to study the redox properties of the betamethasone-clotrimazole (CB) matrix.

The carbon graphite working electrode surface was modified using the betamethasone -clotrimazole matrix. The modified electrode is shown to display the redox properties of the modifying matrix. It is observed that the CB is very unstable on the electrode surface and not completely surface attached. This is confirmed by the data obtained from anodic peak current and scan rate values.

The redox peaks are attributed to the imidazole derivatives from clotrimazole.

CB on bentonite host matrix modified electrode, gave a redox profile with enhanced faradaic quality.

Those cases where the CB was mixed with bentonite to form a composite mixture, which was then used as electrode modification material yielded well defined redox peaks for CB.

P-Aminophenol appears to facilitate the CB redox process through the removal of oxidative stress associated with the redox process.

The improved redox properties of CB on bentonite matrix are attributed to increased physical surface area rather than an incorporation of CB into the  and  layers in the montmorillonite.

Keywords: Cyclic voltammetry, surface modified electrodes, betamethasone, clotrimazole, imidazole, host-matrix, bentonite, p-aminophenol


How to Cite

Orata, D. O., Ngigi, D. G., & Kariuki, D. K. (2022). Improved Faradaic Quality of Betamethasone-clotrimazole Redox Profile on A Bentonite Modified Carbon Graphite Working Electrode. Asian Journal of Pure and Applied Mathematics, 4(1), 243–255. Retrieved from https://globalpresshub.com/index.php/AJPAM/article/view/1541

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