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Tracheobronchial Non-Hodgkin Lymphoma (NHL) is a rare tumor with very few cases reported in medical literature. These tumors typically present as endobronchial mass and/or mucosal infiltration together with lymphadenopathy. They are often misdiagnosed as asthma or chronic obstructive pulmonary disease. Involvement of central airway can cause respiratory failure making treatment difficult, leading to poor prognosis. Histopathological examination is often necessary for definitive diagnosis. These tumors have been a topic of interest due to the challenge they pose to early diagnosis and management Here, we report a uncommon case of primary tracheobronchial NHL and complications encountered during management. This case illustrates that NHL should also be considered as a differential diagnosis in patient who present with central airway obstruction.
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